Biomarkers for Individual Susceptibility to Carcinogenic Agents: Excretion and Carcinogenic Risk of Benzo[a]pyrene Metabolites

Biomarkers for individual susceptibility to carcinogenic agents: excretion and carcinogenic risk of benzo[a]pyrene metabolites.

In rats exposed to a single intraperitoneal dose of 200 mg/kg of the environmental carcinogen benzo[a]pyrene (BP) in sunflower oil, significant individual variations in excretion of the BP activation (BP-7,8-diol) and deactivation (3-OH-BP) derivatives were found. Most rats developed peritoneal sarcomas. Only the levels of BP-7,8-diol excreted in the urine correlated directly with the latency o...

Carcinogenic and Non-Carcinogenic Risk Assessment of Some Heavy Metals Due to Consumption of Raisin Produced in Malayer City

Carcinogenic and Non-Carcinogenic Risk Assessment of Some Heavy Metals Due to Consumption of Raisin Produced in Malayer City Eisa solgi1*, Tarokh khodadadi2 1Associate Professor, Department of Environment, Faculty of Natural Resources and Environment,  Malayer University 2Ph.D. Student of Environmental Pollution, Faculty of Natural Resources and Environment, Malayer University Abstract In...

Physical and chemical agents and carcinogenic risk.

Carcinogenic Chemical Agents *

Cancer is a disease which has long been shrouded in mystery, but our knowledge of its intricacies has been extended in numerous directions by investigations carried on in all parts of the world by workers in many branches of science. Yet it remains true that in general we are not able to explain the origin of cancer, and the methods of treatment at present available are pitifully inadequate. Th...

evaluation of exposure to carcinogenic agents in tehran citizens

background and purpose: today, one of the major health problems worldwide is cancer. several factors are involved in cancer incidence; however, the role of environmental factors is more prominent. modifying these factors and changing them into proper behavior can have a fundamental role in preventing cancer. accordingly, this study was conducted to evaluate the exposure to carcinogenic agents i...